Unfortunately, early, localized, curable prostate cancer has no symptoms. Advanced disease can lead to slowing of the urinary stream, retention of urine, and blood in the urine. It is important, however, to remember that BPH can also cause these symptoms. Metastatic prostate cancer (cancer that has spread to other parts of the body) may result in bone pain, weight loss, and fatigue. LOCALIZED, CURABLE PROSTATE CANCER IS A SILENT DISEASE!